| Player, School | Gms | Comp | Att | INT | Yards | TD |
| *Nathan Grimmett, Summers County | 11 | 142 | 250 | 10 | 2,287 | 26 |
| *Will Fenton, Fayetteville | 11 | 92 | 158 | 4 | 1,800 | 28 |
| Cody Fuller, Bluefield | 10 | 103 | 179 | 9 | 1,533 | 15 |
| *Tate Mayes, Nicholas County | 11 | 71 | 150 | 8 | 1,516 | 23 |
| Elijah Collier, Mount View | 10 | 73 | 171 | 9 | 1,139 | 14 |
| Curtis Gray, Midland Trail | 10 | 36 | 86 | 2 | 729 | 11 |
| *Tyler Haga, Independence | 11 | 38 | 69 | 5 | 707 | 5 |
| Hunter Bevins, Greenbrier West | 9 | 47 | 124 | 4 | 678 | 4 |
| Josh Morgan, Westside | 10 | 42 | 79 | 2 | 660 | 6 |
| Joe Cantley, Shady Spring | 8 | 50 | 124 | 5 | 579 | 3 |
| Hunter Weis, Greenbrier East | 10 | 49 | 96 | 5 | 576 | 4 |
| Hunter Hall, Wyoming East | 6 | 35 | 71 | 5 | 537 | 7 |
| Sutton Radfford, Woodrow Wilson | 8 | 37 | 92 | 6 | 529 | 2 |
| *Evan Beasley, James Monroe | 11 | 24 | 52 | 2 | 527 | 5 |
| Shane Lipps, Richwood | 8 | 44 | 117 | 10 | 507 | 6 |
| Keith Sexton, Shady Spring | 8 | 28 | 58 | 3 | 504 | 7 |
| Jacob Bailey, Liberty | 10 | 35 | 74 | 7 | 462 | 7 |
| Bradie Vance, Westside | 6 | 22 | 43 | 2 | 453 | 6 |
| Devin Persinger, Greenbrier East | 10 | 9 | 19 | 3 | 289 | 3 |
| Christian Shafer, Princeton | 6 | 21 | 52 | 4 | 283 | 1 |
| Jared Hamm, Princeton | 10 | 19 | 44 | 1 | 224 | 1 |
| Tucker Lilly, Summers County | 10 | 5 | 15 | 0 | 171 | 3 |
| Grant Mohler, James Monroe | 10 | 4 | 6 | 2 | 100 | 1 |
| *includes playoff game |